Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction

Expression of CysLT2 receptors in asthma lung, and their possible role in bronchoconstriction

Background: The expression and functional role of CysLT2 receptors in asthma have not been clarified. In this study, we evaluated CysLT2 receptors expression, and effects of CysLT2-and CysLT1/2-receptor antagonists on antigen-induced bronchoconstriction using isolated lung tissues from both asthma a...

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Bibliographic Details
Main Authors: Tomohiko Sekioka, Michiaki Kadode, Masanori Fujii, Kazuhito Kawabata, Takashi Abe, Michiaki Horiba, Shigekatsu Kohno, Takeshi Nabe
Format: Article
Language:English
Published: Elsevier 2015-10-01
Series:Allergology International
Subjects:
Airway smooth muscle
Anti-asthma drugs
CysLT receptors
Cysteinyl leukotrienes
Leukotriene receptor antagonist
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015001069

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http://www.sciencedirect.com/science/article/pii/S1323893015001069

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