Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases

Functional enrichment of alternative splicing events with NEASE reveals insights into tissue identity and diseases

Abstract Alternative splicing (AS) is an important aspect of gene regulation. Nevertheless, its role in molecular processes and pathobiology is far from understood. A roadblock is that tools for the functional analysis of AS-set events are lacking. To mitigate this, we developed NEASE, a tool integr...

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Bibliographic Details
Main Authors: Zakaria Louadi, Maria L. Elkjaer, Melissa Klug, Chit Tong Lio, Amit Fenn, Zsolt Illes, Dario Bongiovanni, Jan Baumbach, Tim Kacprowski, Markus List, Olga Tsoy
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Genome Biology
Subjects:
Alternative splicing
Differential splicing
Functional enrichment
Systems biology
Protein-protein interactions
Disease pathways
Online Access:https://doi.org/10.1186/s13059-021-02538-1

Internet

https://doi.org/10.1186/s13059-021-02538-1

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