B and T Cell Bi-Cistronic Multiepitopic Vaccine Induces Broad Immunogenicity and Provides Protection Against SARS-CoV-2

B and T Cell Bi-Cistronic Multiepitopic Vaccine Induces Broad Immunogenicity and Provides Protection Against SARS-CoV-2

Background: The COVID-19 pandemic, caused by SARS-CoV-2, has highlighted the need for vaccines targeting both neutralizing antibodies (NAbs) and long-lasting cross-reactive T cells covering multiple viral proteins to provide broad and durable protection against emerging variants. Methods: To address...

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Bibliographic Details
Main Authors: Beatriz Perdiguero, Enrique Álvarez, Laura Marcos-Villar, Laura Sin, María López-Bravo, José Ramón Valverde, Carlos Óscar S. Sorzano, Michela Falqui, Rocío Coloma, Mariano Esteban, Susana Guerra, Carmen Elena Gómez
Format: Article
Language:English
Published: MDPI AG 2024-10-01
Series:Vaccines
Subjects:
SARS-CoV-2
vaccine
multiepitopic protein
DNA and MVA vectors
innate response
cellular response
Online Access:https://www.mdpi.com/2076-393X/12/11/1213

Internet

https://www.mdpi.com/2076-393X/12/11/1213

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