TransCent: Computational enzyme design by transferring active sites and considering constraints relevant for catalysis

<p>Abstract</p> <p>Background</p> <p>Computational enzyme design is far from being applicable for the general case. Due to computational complexity and limited knowledge of the structure-function interplay, heuristic methods have to be used.</p> <p>Results&l...

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Bibliographic Details
Main Authors: Sterner Reinhard, Bocola Marco, Neudert Gerd, Enkler Nils, Fischer André, Merkl Rainer
Format: Article
Language:English
Published: BMC 2009-02-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/10/54