New Gemcitabine Derivatives as Potent in vitro α-Glucosidase Inhibitors

In this work, new heterocyclic compounds 1,2,3-triazoline derivatives starting from gemcitabine were synthesized. At first, gemcitabine was converted to 2-azido gemcitabine (G) through the reaction of gemcitabine with sodium azide. 1,2,3-Triazolines were prepared from the reaction of 2-azido gemcita...

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Bibliographic Details
Main Authors: Farked Wahoodi Salman, Ahmed Jasim Twayej, Hayder Ahmed Shaheed, Ali Jabbar Radhi
Format: Article
Language:English
Published: Tsinghua University Press 2019-03-01
Series:Nano Biomedicine and Engineering
Subjects:
Online Access:https://www.sciopen.com/article/10.5101/nbe.v11i1.p84-90