Imaging and biopsy of HIV-infected individuals undergoing analytic treatment interruption

BackgroundHIV persistence during antiretroviral therapy (ART) is the principal obstacle to cure. Lymphoid tissue is a compartment for HIV, but mechanisms of persistence during ART and viral rebound when ART is interrupted are inadequately understood. Metabolic activity in lymphoid tissue of patients...

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Main Authors: Chuen-Yen Lau, Matthew A. Adan, Jessica Earhart, Cassie Seamon, Thuy Nguyen, Ariana Savramis, Lindsey Adams, Mary-Elizabeth Zipparo, Erin Madeen, Kristi Huik, Zehava Grossman, Benjamin Chimukangara, Wahyu Nawang Wulan, Corina Millo, Avindra Nath, Bryan R. Smith, Ana M. Ortega-Villa, Michael Proschan, Bradford J. Wood, Dima A. Hammoud, Frank Maldarelli
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2022.979756/full