High glucose conditioned neonatal astrocytes results in impaired mitogenic activity in cerebral microvessel endothelial cells in co-culture

Angiogenesis is a highly complex and coordinated process in the brain. Under normal conditions, it is a vital process in growth and development, but under adverse conditions such as diabetes mellitus, it can lead to severe pathology. Astrocytes are a key constituent of the neurovascular unit and con...

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Bibliographic Details
Main Authors: Susan Cohen, Qiuli Liu, Matthew Wright, Jodi Garvin, Kevin Rarick, David Harder
Format: Article
Language:English
Published: Elsevier 2019-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018380642