Deletion of FGF9 in GABAergic neurons causes epilepsy

Abstract Fibroblast growth factor 9 (FGF9) has long been assumed to modulate multiple biological processes, yet very little is known about the impact of FGF9 on neurodevelopment. Herein, we found that loss of Fgf9 in olig1 progenitor cells induced epilepsy in mice, with pathological changes in the c...

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Bibliographic Details
Main Authors: Moran Guo, Can Cui, Xueqin Song, Lijing Jia, Duan Li, Xiuli Wang, Hui Dong, Yanqin Ma, Yaling Liu, Zhiqiang Cui, Le Yi, Zhongyao Li, Yue Bi, Yuanyuan Li, Yakun Liu, Weisong Duan, Chunyan Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03478-1