The WMI Rat of Premature Cognitive Aging Presents Intrinsic Vulnerability to Oxidative Stress in Primary Neurons and Astrocytes Compared to Its Nearly Isogenic WLI Control

The WMI Rat of Premature Cognitive Aging Presents Intrinsic Vulnerability to Oxidative Stress in Primary Neurons and Astrocytes Compared to Its Nearly Isogenic WLI Control

The primary neuronal and astrocyte culture described here is from the stress-hyperreactive Wistar Kyoto (WKY) More Immobile (WMI) rat with premature aging-related memory deficit, and its nearly isogenic control, the Less Immobile (WLI) strain. Primary WMI hippocampal neurons and cortical astrocytes...

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Bibliographic Details
Main Authors: Adriana Ferreira, Aspen Harter, Sana Afreen, Karoly Kanai, Sandor Batori, Eva E. Redei
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:International Journal of Molecular Sciences
Subjects:
oxidative stress
mitochondrial dysfunction
gene expressions
strain differences
Online Access:https://www.mdpi.com/1422-0067/25/3/1692

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https://www.mdpi.com/1422-0067/25/3/1692

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