Modulating Properties of Piroxicam, Meloxicam and Oxicam Analogues against Macrophage-Associated Chemokines in Colorectal Cancer

Modulating Properties of Piroxicam, Meloxicam and Oxicam Analogues against Macrophage-Associated Chemokines in Colorectal Cancer

The mechanisms underlying the antineoplastic effects of oxicams have not been fully elucidated. We aimed to assess the effect of classic and novel oxicams on the expression/secretion of macrophage-associated chemokines (RTqPCR/Luminex xMAP) in colorectal adenocarcinoma cells, and on the expression o...

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Bibliographic Details
Main Authors: Paulina Lewandowska, Izabela Szczuka, Iwona Bednarz-Misa, Berenika M. Szczęśniak-Sięga, Katarzyna Neubauer, Magdalena Mierzchała-Pasierb, Marek Zawadzki, Wojciech Witkiewicz, Małgorzata Krzystek-Korpacka
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
non-steroidal anti-inflammatory drugs (NSAIDs)
drug repurposing
monocyte chemoattractant protein (MCP)
macrophage inflammatory protein (MIP)
immunotherapy
piroxicam
Online Access:https://www.mdpi.com/1420-3049/26/23/7375

Internet

https://www.mdpi.com/1420-3049/26/23/7375

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