Modulating Properties of Piroxicam, Meloxicam and Oxicam Analogues against Macrophage-Associated Chemokines in Colorectal Cancer
The mechanisms underlying the antineoplastic effects of oxicams have not been fully elucidated. We aimed to assess the effect of classic and novel oxicams on the expression/secretion of macrophage-associated chemokines (RTqPCR/Luminex xMAP) in colorectal adenocarcinoma cells, and on the expression o...
Main Authors: | Paulina Lewandowska, Izabela Szczuka, Iwona Bednarz-Misa, Berenika M. Szczęśniak-Sięga, Katarzyna Neubauer, Magdalena Mierzchała-Pasierb, Marek Zawadzki, Wojciech Witkiewicz, Małgorzata Krzystek-Korpacka |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-12-01
|
Series: | Molecules |
Subjects: | |
Online Access: | https://www.mdpi.com/1420-3049/26/23/7375 |
Similar Items
-
Heat Shock Proteins HSPA1 and HSP90AA1 Are Upregulated in Colorectal Polyps and Can Be Targeted in Cancer Cells by Anti-Inflammatory Oxicams with Arylpiperazine Pharmacophore and Benzoyl Moiety Substitutions at Thiazine Ring
by: Izabela Szczuka, et al.
Published: (2021-10-01) -
Interaction of Oxicam Derivatives with the Artificial Models of Biological Membranes—Calorimetric and Fluorescence Spectroscopic Study
by: Jadwiga Maniewska, et al.
Published: (2022-08-01) -
Comparison of oral and sublingual piroxicam for management of postoperative pain after mandibular third molar surgery: A prospective, randomized study
by: Shruti Shashikant Phulgirkar, et al.
Published: (2016-01-01) -
Selective in vitro cytotoxic effects of piroxicam and mefenamic acid on several cancer cells lines.
by: Somchit, M.N, et al.
Published: (2009) -
Solubility Enhancement of Betamethasone, Meloxicam and Piroxicam by Use of Choline-Based Deep Eutectic Solvents
by: Salva Golgoun, et al.
Published: (2021-03-01)