Differentiated HT22 cells as a novel model for in vitro screening of serotonin reuptake inhibitors

The mouse hippocampal neuronal cell line HT22 is frequently used as an in vitro model to investigate the role of hippocampal cholinergic neurons in cognitive functions. HT22 cells are derived from hippocampal neuronal HT4 cells. However, whether these cells exhibit the serotonergic neuronal phenotyp...

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Bibliographic Details
Main Authors: Juhee Lim, Yeojin Bang, Kyeong-Man Kim, Hyun Jin Choi
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1062650/full