Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polychlorinated Biphenyls Mixture in the Juvenile Mouse

Sex and Genotype Modulate the Dendritic Effects of Developmental Exposure to a Human-Relevant Polychlorinated Biphenyls Mixture in the Juvenile Mouse

While many neurodevelopmental disorders (NDDs) are thought to result from interactions between environmental and genetic risk factors, the identification of specific gene-environment interactions that influence NDD risk remains a critical data gap. We tested the hypothesis that polychlorinated biphe...

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Bibliographic Details
Main Authors: Kimberly P. Keil Stietz, Sunjay Sethi, Carolyn R. Klocke, Tryssa E. de Ruyter, Machelle D. Wilson, Isaac N. Pessah, Pamela J. Lein
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Neuroscience
Subjects:
FMR1 premutation
gene–environment interaction
Golgi stain
neurodevelopmental disorders
ryanodine receptor
Sholl analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.766802/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.766802/full

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