Tackling Immunotherapy Resistance: Developing Rational Combinations of Immunotherapy and Targeted Drugs

Mechanisms of resistance to immunotherapies are multiple and complex with components intrinsic to the tumor cell and within the immune microenvironment. We review evidence of the interaction of tumor cell signaling pathways with immune pathways and the role this plays in de novo and acquired resista...

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Bibliographic Details
Main Authors: Elena Cojocaru, Mariana Scaranti, Anna Minchom
Format: Article
Language:English
Published: Innovative Healthcare Institute 2019-05-01
Series:Journal of Immunotherapy and Precision Oncology
Subjects:
Online Access:https://jipo.org/doi/pdf/10.4103/JIPO.JIPO_24_18