Topological analysis of interaction patterns in cancer-specific gene regulatory network: persistent homology approach

Abstract In this study, we investigated cancer cellular networks in the context of gene interactions and their associated patterns in order to recognize the structural features underlying this disease. We aim to propose that the quest of understanding cancer takes us beyond pairwise interactions bet...

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Bibliographic Details
Main Authors: Hosein Masoomy, Behrouz Askari, Samin Tajik, Abbas K. Rizi, G. Reza Jafari
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-94847-5