Uncovering ferroptosis in Parkinson’s disease via bioinformatics and machine learning, and reversed deducing potential therapeutic natural products

Uncovering ferroptosis in Parkinson’s disease via bioinformatics and machine learning, and reversed deducing potential therapeutic natural products

Objective: Ferroptosis, a novel form of cell death, is closely associated with excessive iron accumulated within the substantia nigra in Parkinson’s disease (PD). Despite extensive research, the underlying molecular mechanisms driving ferroptosis in PD remain elusive. Here, we employed a bioinformat...

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Bibliographic Details
Main Authors: Peng Wang, Qi Chen, Zhuqian Tang, Liang Wang, Bizhen Gong, Min Li, Shaodan Li, Minghui Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-07-01
Series:Frontiers in Genetics
Subjects:
Parkinson’s disease
ferroptosis
transcriptomics
machine learning
natural product
ingredient
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2023.1231707/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2023.1231707/full

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