Sodium Butyrate Enhances Curcuminoids Permeability through the Blood-Brain Barrier, Restores Wnt/β-Catenin Pathway Antagonists Gene Expression and Reduces the Viability of Glioblastoma Cells

Sodium Butyrate Enhances Curcuminoids Permeability through the Blood-Brain Barrier, Restores Wnt/β-Catenin Pathway Antagonists Gene Expression and Reduces the Viability of Glioblastoma Cells

Glioblastoma (GBM) is an extremely aggressive brain tumor awaiting novel, efficient, and minimally toxic treatment. Curcuminoids (CCM), polyphenols from <i>Curcuma longa</i>, and sodium butyrate (NaBu), a histone deacetylase inhibitor naturally occurring in the human body, await elucidat...

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Bibliographic Details
Main Authors: Aleksandra Majchrzak-Celińska, Robert Kleszcz, Anna Stasiłowicz-Krzemień, Judyta Cielecka-Piontek
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
curcuminoids
sodium butyrate
glioblastoma
cell cycle
apoptosis
reactive oxygen species
Online Access:https://www.mdpi.com/1422-0067/22/20/11285

Internet

https://www.mdpi.com/1422-0067/22/20/11285

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