Behavioral pattern separation and cognitive flexibility are enhanced in a mouse model of increased lateral entorhinal cortex-dentate gyrus circuit activity

Behavioral pattern separation and cognitive flexibility are essential cognitive abilities that are disrupted in many brain disorders. A better understanding of the neural circuitry involved in these abilities will open paths to treatment. In humans and mice, discrimination and adaptation rely on the...

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Bibliographic Details
Main Authors: Sanghee Yun, Ivan Soler, Fionya H. Tran, Harley A. Haas, Raymon Shi, Grace L. Bancroft, Maiko Suarez, Christopher R. de Santis, Ryan P. Reynolds, Amelia J. Eisch
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2023.1151877/full