Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma

Targeted Lipidomic Analysis of Aqueous Humor Reveals Signaling Lipid-Mediated Pathways in Primary Open-Angle Glaucoma

Primary open-angle glaucoma (POAG) is characterized by degeneration of retinal ganglion cells associated with an increase in intraocular pressure (IOP) due to hindered aqueous humor (AH) drainage through the trabecular meshwork and uveoscleral pathway. Polyunsaturated fatty acids and oxylipins are s...

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Bibliographic Details
Main Authors: Nadezhda V. Azbukina, Dmitry V. Chistyakov, Sergei V. Goriainov, Vladislav I. Kotelin, Elena V. Fedoseeva, Sergey Yu. Petrov, Marina G. Sergeeva, Elena N. Iomdina, Evgeni Yu. Zernii
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biology
Subjects:
primary open-angle glaucoma
aqueous humor
tear fluid
lipidomics
signaling lipids
polyunsaturated fatty acids
Online Access:https://www.mdpi.com/2079-7737/10/7/658

Internet

https://www.mdpi.com/2079-7737/10/7/658

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