NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo

NSC19723, a Thiacetazone-Like Benzaldehyde Thiosemicarbazone Improves the Efficacy of TB Drugs In Vitro and In Vivo

ABSTRACT The complexity and duration of tuberculosis (TB) treatment contributes to the emergence of drug resistant tuberculosis (DR-TB) and drug-associated side effects. Alternate chemotherapeutic agents are needed to shorten the time and improve efficacy of current treatment. In this study, we have...

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Bibliographic Details
Main Authors: Padam Singh, Srishti Rawat, Ashish Kumar Agrahari, Manisha Singh, Saurabh Chugh, Sudagar Gurcha, Albel Singh, Katherine Abrahams, Gurdyal S. Besra, Shailendra Asthana, Diwan S. Rawat, Ramandeep Singh
Format: Article
Language:English
Published: American Society for Microbiology 2022-12-01
Series:Microbiology Spectrum
Subjects:
Mycobacterium tuberculosis
NSC19723
HadABC
synergy
thiacetazone
Online Access:https://journals.asm.org/doi/10.1128/spectrum.02592-22

Internet

https://journals.asm.org/doi/10.1128/spectrum.02592-22

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