Selective activation of STAT3 and STAT5 dictates the fate of myeloid progenitor cells

Abstract The molecular programs that govern the directed differentiation of myeloid progenitor cells are still poorly defined. Using a previously established immortalized, phenotypically normal myeloid progenitor cell model mEB8-ER, we unveil a new mechanism mediated by STAT5 and STAT3 at a bifurcat...

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Bibliographic Details
Main Authors: Meichao Zhang, Yiling Meng, Yingxia Ying, Pingting Zhou, Suning Zhang, Yong Fang, Yuan Yao, Dong Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01575-y