A multiomic atlas of the aging hippocampus reveals molecular changes in response to environmental enrichment

Abstract Aging involves the deterioration of organismal function, leading to the emergence of multiple pathologies. Environmental stimuli, including lifestyle, can influence the trajectory of this process and may be used as tools in the pursuit of healthy aging. To evaluate the role of epigenetic me...

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Bibliographic Details
Main Authors: Raúl F. Pérez, Patricia Tezanos, Alfonso Peñarroya, Alejandro González-Ramón, Rocío G. Urdinguio, Javier Gancedo-Verdejo, Juan Ramón Tejedor, Pablo Santamarina-Ojeda, Juan José Alba-Linares, Lidia Sainz-Ledo, Annalisa Roberti, Virginia López, Cristina Mangas, María Moro, Elisa Cintado Reyes, Pablo Muela Martínez, Mar Rodríguez-Santamaría, Ignacio Ortea, Ramón Iglesias-Rey, Juan Castilla-Silgado, Cristina Tomás-Zapico, Eduardo Iglesias-Gutiérrez, Benjamín Fernández-García, Jose Vicente Sanchez-Mut, José Luis Trejo, Agustín F. Fernández, Mario F. Fraga
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-49608-z