Crystal Structure Analysis of the First Discovered Stability-Enhanced Solid State of Tenofovir Disoproxil Free Base Using Single Crystal X-ray Diffraction

Crystal Structure Analysis of the First Discovered Stability-Enhanced Solid State of Tenofovir Disoproxil Free Base Using Single Crystal X-ray Diffraction

Tenofovir disoproxil (TD), an anti-virus drug, is currently marketed under its most stable form, Form-I of Tenofovir disoproxil fumarate (TDF). However, studies regarding the properties of TD free base crystal as a promising drug as well as its crystal structure have not yet been reported. This assu...

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Bibliographic Details
Main Authors: Ji-Hun An, Alice Nguvoko Kiyonga, Woojin Yoon, Hyung Chul Ryu, Jae-Sun Kim, Chaeri Kang, Minho Park, Hoseop Yun, Kiwon Jung
Format: Article
Language:English
Published: MDPI AG 2017-07-01
Series:Molecules
Subjects:
Tenofovir disoproxil
crystal structure
stability
solubility
active pharmaceutical ingredients
Online Access:https://www.mdpi.com/1420-3049/22/7/1182

Internet

https://www.mdpi.com/1420-3049/22/7/1182

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