Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge

Synthetic nucleic acid antibody prophylaxis confers rapid and durable protective immunity against Zika virus challenge

Significant concerns have arisen over the past 3 y from the increased global spread of the mosquito-borne flavivirus, Zika. Accompanying this spread has been an increase in cases of the devastating birth defect microcephaly as well as of Guillain–Barré syndrome in adults in many affected countries....

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Bibliographic Details
Main Authors: Hyeree Choi, Sagar B. Kudchodkar, Emma L. Reuschel, Kanika Asija, Piyush Borole, Sangya Agarwal, Lucas Van Gorder, Charles C. Reed, Gayathri Gulendran, Stephanie Ramos, Kate E. Broderick, J Joseph Kim, Kenneth E. Ugen, Gary Kobinger, Don L. Siegel, David B. Weiner, Kar Muthumani
Format: Article
Language:English
Published: Taylor & Francis Group 2020-04-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
zika virus
antibodies
dmab-dna encoded monoclonal antibodies
vaccination
immunotherapy
dna vaccine
Online Access:http://dx.doi.org/10.1080/21645515.2019.1688038

Internet

http://dx.doi.org/10.1080/21645515.2019.1688038

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