Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

Regulation of IκBα expression involves both NF-κB and the MAP kinase signaling pathways

<p>Abstract</p> <p>IκBα is an inhibitor of the nuclear transcription factor NF-κB. Binding of IκBα to NF-κB inactivates the transcriptional activity of NF-κB. Expression of IκBα itself is regulated by NF-κB, which provides auto-regulation of this signaling pathway. Here we present...

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Bibliographic Details
Main Authors: Sambucetti Lidia C, Zhu Lingyun, Ahsan Muhammad H, Zhang Ning, Purchio Anthony F, West David B
Format: Article
Language:English
Published: BMC 2005-10-01
Series:Journal of Inflammation
Subjects:
IkappaB
NF-κB
MAP kinase
bortezomib
lipopolysaccharide
bioluminescent imaging
Online Access:http://www.journal-inflammation.com/content/2/1/10

Internet

http://www.journal-inflammation.com/content/2/1/10

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