A circuitous route for in vitro multi-enzyme cascade production of cytidine triphosphate to overcome the thermodynamic bottleneck

A circuitous route for in vitro multi-enzyme cascade production of cytidine triphosphate to overcome the thermodynamic bottleneck

Abstract Cytidine triphosphate (CTP), as a substance involved in the metabolism of phospholipids, proteins and nucleic acids, has precise drug effects and is a direct precursor for the synthesis of drugs such as citicoline. In this study, we established an in vitro six-enzyme cascade system to gener...

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Xehetasun bibliografikoak
Egile Nagusiak: Zonglin Li, Yahui Zhong, Zhoulei Qing, Zhimin Li
Formatua: Artikulua
Hizkuntza:English
Argitaratua: SpringerOpen 2024-01-01
Saila:Bioresources and Bioprocessing
Gaiak:
CTP
In vitro
Multi-enzymatic cascade
Circuitous route
Directed evolution
CTP synthetase
Sarrera elektronikoa:https://doi.org/10.1186/s40643-023-00724-6

Internet

https://doi.org/10.1186/s40643-023-00724-6

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