Three-Dimensional Cell Metabolomics Deciphers the Anti-Angiogenic Properties of the Radioprotectant Amifostine

Three-Dimensional Cell Metabolomics Deciphers the Anti-Angiogenic Properties of the Radioprotectant Amifostine

Aberrant angiogenesis is a hallmark for cancer and inflammation, a key notion in drug repurposing efforts. To delineate the anti-angiogenic properties of amifostine in a human adult angiogenesis model via 3D cell metabolomics and upon a stimulant-specific manner, a 3D cellular angiogenesis assay tha...

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Bibliographic Details
Main Authors: Theodora Katsila, Styliani A. Chasapi, Jose Carlos Gomez Tamayo, Constantina Chalikiopoulou, Eleni Siapi, Giorgos Moros, Panagiotis Zoumpoulakis, Georgios A. Spyroulias, Dimitrios Kardamakis
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Cancers
Subjects:
amifostine
3D cellular angiogenesis assay
metabolomics
drug repurposing
radioprotection
anti-angiogenesis
Online Access:https://www.mdpi.com/2072-6694/13/12/2877

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https://www.mdpi.com/2072-6694/13/12/2877

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