A multiomics analysis of direct interkingdom dynamics between influenza A virus and Streptococcus pneumoniae uncovers host-independent changes to bacterial virulence fitness.

<h4>Background</h4>For almost a century, it has been recognized that influenza A virus (IAV) infection can promote the development of secondary bacterial infections (SBI) mainly caused by Streptococcus pneumoniae (Spn). Recent observations have shown that IAV is able to directly bind to...

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Bibliographic Details
Main Authors: Maryann P Platt, Yi-Han Lin, Trevor Penix, Rosana Wiscovitch-Russo, Isha Vashee, Chris A Mares, Jason W Rosch, Yanbao Yu, Norberto Gonzalez-Juarbe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011020