Expansion of T regulatory lymphocytes by murine bone marrow dendritic cells previously stimulated with Anisakis simplex larval antigens

Expansion of T regulatory lymphocytes by murine bone marrow dendritic cells previously stimulated with Anisakis simplex larval antigens

BACKGROUND Anisakis simplex antigens present immunomodulatory properties by the induction of tolerogenic dendritic cells (DCs) in mice. OBJECTIVES To study the capacity of DCs stimulated with A. simplex excretory-secretory (ES) or crude extract (CE) to generate Tregs. To investigate in vitro effec...

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Bibliographic Details
Main Authors: Vega Zamora, Marta Rodero, Alexandra Ibáñez-Escribano, Juan C Andreu-Ballester, Susana Mendez, Carmen Cuéllar
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2021-02-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Anisakis simplex
mice
tolerogenic dendritic cells
T regulatory cells
IL-10
mitochondrial activity
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762021000100300&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762021000100300&tlng=en

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