Function of astrocyte MyD88 in high-fat-diet-induced hypothalamic inflammation

Function of astrocyte MyD88 in high-fat-diet-induced hypothalamic inflammation

Abstract Background A growing body of evidence shows that hypothalamic inflammation is an important factor in the initiation of obesity. In particular, reactive gliosis accompanied by inflammatory responses in the hypothalamus are pivotal cellular events that elicit metabolic abnormalities. In this...

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Bibliographic Details
Main Authors: Sungho Jin, Kwang Kon Kim, Byong Seo Park, Dong Hee Kim, Bora Jeong, Dasol Kang, Tae Hwan Lee, Jeong Woo Park, Jae Geun Kim, Byung Ju Lee
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Journal of Neuroinflammation
Subjects:
Myeloid differentiation primary response 88
Hypothalamus
Reactive gliosis
Obesity
Leptin resistance
High-fat diet
Online Access:http://link.springer.com/article/10.1186/s12974-020-01846-w

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http://link.springer.com/article/10.1186/s12974-020-01846-w

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