Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression

Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression

Aspalathin (ASP) can protect H9c2 cardiomyocytes against high glucose (HG)-induced shifts in myocardial substrate preference, oxidative stress, and apoptosis. The protective mechanism of ASP remains unknown. However, as one of possible, it is well known that phytochemical flavonoids reduce oxidative...

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Bibliographic Details
Main Authors: Phiwayinkosi V. Dludla, Christo J. F. Muller, Elizabeth Joubert, Johan Louw, M. Faadiel Essop, Kwazi B. Gabuza, Samira Ghoor, Barbara Huisamen, Rabia Johnson
Format: Article
Language:English
Published: MDPI AG 2017-01-01
Series:Molecules
Subjects:
diabetes mellitus
cardiomyopathy
hyperglycemia
oxidative stress
aspalathin
Nrf2
Online Access:http://www.mdpi.com/1420-3049/22/1/129

Internet

http://www.mdpi.com/1420-3049/22/1/129

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