Integrative analysis of single-cell transcriptomics reveals age-associated immune landscape of glioblastoma

Integrative analysis of single-cell transcriptomics reveals age-associated immune landscape of glioblastoma

Glioblastoma (GBM) is the most malignant tumor in center nervous system. Clinical statistics revealed that senior GBM patients had a worse overall survival (OS) comparing with that of patients in other ages, which is mainly related with tumor microenvironment including tumor-associated immune cells...

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Bibliographic Details
Main Authors: Songang Wu, Xuewen Li, Fan Hong, Qiang Chen, Yingying Yu, Shuanghui Guo, Yuanyuan Xie, Naian Xiao, Xuwen Kong, Wei Mo, Zhanxiang Wang, Shaoxuan Chen, Feng Zeng
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
age
tumor heterogeneity
single-cell RNA sequencing (scRNA-seq)
immune microenvironment
GBM
monocyte-derived macrophage (MDM)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1028775/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1028775/full

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