Brønsted acid-enhanced copper-catalyzed atroposelective cycloisomerization to axially chiral arylquinolizones via dearomatization of pyridine
Methods to assemble axially chiral biaryl molecules with nitrogen-containing heterocycles can have implications in ligand development for homogeneous catalysis. Here the authors report enantioselective syntheses of axially chiral arylquinolizones, via an intramolecular atroposelective cycloisomeriza...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2022-01-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-022-27989-3 |