Antagonism of interferon signaling by fibroblast growth factors promotes viral replication

Antagonism of interferon signaling by fibroblast growth factors promotes viral replication

Abstract Fibroblast growth factors (FGFs) play key roles in the pathogenesis of different human diseases, but the cross‐talk between FGFs and other cytokines remains largely unexplored. We identified an unexpected antagonistic effect of FGFs on the interferon (IFN) signaling pathway. Genetic or phar...

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Bibliographic Details
Main Authors: Luigi Maddaluno, Corinne Urwyler, Theresa Rauschendorfer, Michael Meyer, Debora Stefanova, Roman Spörri, Mateusz Wietecha, Luca Ferrarese, Diana Stoycheva, Daniela Bender, Nick Li, Gerhard Strittmatter, Khondokar Nasirujjaman, Hans‐Dietmar Beer, Peter Staeheli, Eberhard Hildt, Annette Oxenius, Sabine Werner
Format: Article
Language:English
Published: Springer Nature 2020-09-01
Series:EMBO Molecular Medicine
Subjects:
fibroblast growth factor
FGF receptor
Herpes simplex virus
interferon
Zika virus
Online Access:https://doi.org/10.15252/emmm.201911793

Internet

https://doi.org/10.15252/emmm.201911793

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