Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes

Ablation of USP21 in skeletal muscle promotes oxidative fibre phenotype, inhibiting obesity and type 2 diabetes

Abstract Background Skeletal muscle as a metabolic consumer determines systemic energy homeostasis by regulating myofibre type conversion and muscle mass control. Perturbation of the skeletal muscle metabolism elevates the risk of a variety of diseases including metabolic disorders. However, the reg...

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Bibliographic Details
Main Authors: Ayoung Kim, Ja Hyun Koo, Xing Jin, Wondong Kim, Shi‐Young Park, Sunghyouk Park, Eugene P. Rhee, Cheol Soo Choi, Sang Geon Kim
Format: Article
Language:English
Published: Wiley 2021-12-01
Series:Journal of Cachexia, Sarcopenia and Muscle
Subjects:
USP21
Skeletal muscle
Oxidative fibre type
Muscle mass control
Obesity
Diabetes
Online Access:https://doi.org/10.1002/jcsm.12777

Internet

https://doi.org/10.1002/jcsm.12777

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