Elevated serum and urine levels of progranulin (PGRN) as a predictor of microglia activation in the early phase of traumatic brain injury: a further link with the development of neurodegenerative diseases

Elevated serum and urine levels of progranulin (PGRN) as a predictor of microglia activation in the early phase of traumatic brain injury: a further link with the development of neurodegenerative diseases

Traumatic brain injury (TBI) is a frequent finding during forensic autopsies and neuropathological examinations in medico-legal practices. Despite the unprecedented attention currently focused on TBI pathogenesis, there is a need to improve its diagnostics through the use of novel biomarkers to faci...

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Bibliographic Details
Main Authors: Mieszko Olczak, Łukasz A. Poniatowski, Agnieszka Siwińska, Magdalena Kwiatkowska, Dominik Chutorański, Teresa Wierzba-Bobrowicz
Format: Article
Language:English
Published: Termedia Publishing House 2021-03-01
Series:Folia Neuropathologica
Subjects:
progranulin
traumatic brain injury
microglia
serum
urine
neurodegenerative diseases.
Online Access:https://www.termedia.pl/Elevated-serum-and-urine-levels-of-progranulin-PGRN-as-a-predictor-r-nof-microglia-activation-in-the-early-phase-of-traumatic-brain-injury-r-na-further-link-with-the-development-of-neurodegenerative-d,20,43765,1,1.html

Internet

https://www.termedia.pl/Elevated-serum-and-urine-levels-of-progranulin-PGRN-as-a-predictor-r-nof-microglia-activation-in-the-early-phase-of-traumatic-brain-injury-r-na-further-link-with-the-development-of-neurodegenerative-d,20,43765,1,1.html

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