“Pill-in-the-Pocket” Treatment of Propafenone Unmasks ECG Brugada Pattern in an Atrial Fibrillation Patient With a Common SCN5A R1193Q Polymorphism

“Pill-in-the-Pocket” Treatment of Propafenone Unmasks ECG Brugada Pattern in an Atrial Fibrillation Patient With a Common SCN5A R1193Q Polymorphism

Background: “Pill-in-the-pocket” (PIP) treatment with type IC drugs for cardioversion of recent-onset atrial fibrillation (AF) has been recommended in guidelines. Major adverse effects have been often reported, and the underlying mechanisms are proposed to be associated with the genetic backgrounds....

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Bibliographic Details
Main Authors: Linling Li, Yanfei Ruan, Nian Liu, Qianqian Zhao, Mengxia Zhang, Xin Li, Song Zuo, Jiang Le, Kui Wu, Rong Bai, Changsheng Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
Brugada syndrome
atrial fibrillation
SCN5A
polymorphism
propafenone
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00353/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00353/full

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