Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients

Cerebrospinal fluid quinolinic acid is strongly associated with delirium and mortality in hip-fracture patients

BACKGROUND The kynurenine pathway (KP) has been identified as a potential mediator linking acute illness to cognitive dysfunction by generating neuroactive metabolites in response to inflammation. Delirium (acute confusion) is a common complication of acute illness and is associated with increased r...

Full description

Bibliographic Details
Main Authors: Leiv Otto Watne, Christian Thomas Pollmann, Bjørn Erik Neerland, Else Quist-Paulsen, Nathalie Bodd Halaas, Ane-Victoria Idland, Bjørnar Hassel, Kristi Henjum, Anne-Brita Knapskog, Frede Frihagen, Johan Raeder, Aasmund Godø, Per Magne Ueland, Adrian McCann, Wender Figved, Geir Selbæk, Henrik Zetterberg, Evandro F. Fang, Marius Myrstad, Lasse M. Giil
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-01-01
Series:The Journal of Clinical Investigation
Subjects:
Inflammation
Metabolism
Online Access:https://doi.org/10.1172/JCI163472

Internet

https://doi.org/10.1172/JCI163472

Similar Items