Angiotensin II receptor blockade blocker pre-treatment largely prevents injury from gradual renal ablation in rats

Angiotensin II receptor blockade blocker pre-treatment largely prevents injury from gradual renal ablation in rats

Introduction. Reduction in renal mass in rats results in progressive proteinuria, hypertension, focal-segmental glomerulosclerosis (FSG), atrophy of tubules (AT), and interstitial expansion. We reported that slow reduction of renal tissue in rats (slow ablation) ending in the removal of 1.5 kidneys...

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Bibliographic Details
Main Authors: Hye Won Park, Youngki Kim, Kee Hyuck Kim, Hyeon Joo Jeong, Myung-Hee Shin, Silvia Rozen, Michael Mauer
Format: Article
Language:English
Published: SAGE Publications 2007-09-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jrass.2007.022

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https://doi.org/10.3317/jrass.2007.022

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