Tauroursodeoxycholic acid (TUDCA) disparate pharmacological effects to lung tissue-resident memory T cells contribute to alleviated silicosis

Exposure to crystalline silica (CS) results in a persistent pulmonary inflammatory response, which results in abnormal tissue repair and excessive matrix deposition. Due to vague pathogenesis, there is virtually no practical therapeutic approach. Here we showed the pharmacological effects of TUDCA o...

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Bibliographic Details
Main Authors: Chao Li, Yang-yang He, Yu-ting Zhang, Yi-chuan You, Hao-yang Yuan, Yun-geng Wei, Xi Chen, Jie Chen
Format: Article
Language:English
Published: Elsevier 2022-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222005625