TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells

TM4SF1-AS1 inhibits apoptosis by promoting stress granule formation in cancer cells

Abstract Long noncoding RNAs (lncRNAs) play pivotal roles in tumor development. To identify dysregulated lncRNAs in gastric cancer (GC), we analyzed genome-wide trimethylation of histone H3 lysine 4 (H3K4me3) to screen for transcriptionally active lncRNA genes in the non-tumorous gastric mucosa of p...

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Main Authors: Hiroshi Kitajima, Reo Maruyama, Takeshi Niinuma, Eiichiro Yamamoto, Akira Takasawa, Kumi Takasawa, Kazuya Ishiguro, Akihiro Tsuyada, Ryo Suzuki, Gota Sudo, Toshiyuki Kubo, Kei Mitsuhashi, Masashi Idogawa, Shoichiro Tange, Mutsumi Toyota, Ayano Yoshido, Kohei Kumegawa, Masahiro Kai, Kazuyoshi Yanagihara, Takashi Tokino, Makoto Osanai, Hiroshi Nakase, Hiromu Suzuki
Format: Article
Language:English
Published: Nature Publishing Group 2023-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05953-3

Internet

https://doi.org/10.1038/s41419-023-05953-3

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