4369 Reprogramming of vascular smooth muscle cells to multipotent progenitor cells contributes to progression of atherosclerosis

OBJECTIVES/GOALS: Our lab previously identified a population of vascular smooth muscle (SMC)-derived progenitor cells (AdvSca1-SM) which expand robustly in response to disease and can differentiate into multiple cell types. We now aim to define the role of these AdvSca1-SM cells in atherosclerotic p...

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Bibliographic Details
Main Authors: Allison Milfred Dubner, Sizhao Lu, Austin Jolly, Keith Strand, Marie Mutryn, Rebecca Tucker, Karen Moulton, Raphael A. Nemenoff, Mary C.M. Weiser-Evans
Format: Article
Language:English
Published: Cambridge University Press 2020-06-01
Series:Journal of Clinical and Translational Science
Online Access:https://www.cambridge.org/core/product/identifier/S2059866120003155/type/journal_article