Subthalamic nucleus stimulation attenuates motor seizures via modulating the nigral orexin pathway

BackgroundFocal motor seizures that originate in the motor region are a considerable challenge because of the high risk of permanent motor deficits after resection. Deep brain stimulation of the subthalamic nucleus (STN-DBS) is a potential treatment for motor epilepsy that may enhance the antiepilep...

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Bibliographic Details
Main Authors: Tao Xue, Shu Wang, Shujun Chen, Huizhi Wang, Chong Liu, Lin Shi, Yutong Bai, Chunkui Zhang, Chunlei Han, Jianguo Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Neuroscience
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Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.1157060/full