Structure of racemic duloxetine hydrochloride

Structure of racemic duloxetine hydrochloride

Duloxetine hydrochloride (trade name Cymbalta) is marketed as a single enantiomer (S)-N-methyl-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylaminium chloride, C18H20NOS+·Cl−, which is twice as effective as the (R)-enantiomer in serotonin uptake. Here, we report the crystal structure of duloxetine hy...

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Bibliographic Details
Main Authors: Mohan M. Bhadbhade, Jiabin Gao, Anne M. Rich, Christopher E. Marjo
Format: Article
Language:English
Published: International Union of Crystallography 2023-05-01
Series:Acta Crystallographica Section E: Crystallographic Communications
Subjects:
anti-depressant drug
duloxetine
racemate
crystal structure
side chain conformation
molecular packing
Online Access:http://scripts.iucr.org/cgi-bin/paper?S2056989023003353

Internet

http://scripts.iucr.org/cgi-bin/paper?S2056989023003353

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