Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1

Immune suppressive function of IL-1α release in the tumor microenvironment regulated by calpain 1

Interleukin-1α (IL-1α) plays an important role in inflammation and hematopoiesis. Many tumors have increased IL-1α expression. However, the immune regulatory role of secreted IL-1α in tumor development and whether it can be targeted for cancer therapy are still unclear. Here, we found that tumoral-s...

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Bibliographic Details
Main Authors: Dandan Lin, Yu Mei, Lei Lei, Zuhairah Binte Hanafi, Ziqi Jin, Yonghao Liu, Yuan Song, Yinsheng Zhang, Bo Hu, Chunliang Liu, Jinhua Lu, Haiyan Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:OncoImmunology
Subjects:
HCC
IL-1α
MDSC
CALPAIN 1
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2022.2088467

Internet

https://www.tandfonline.com/doi/10.1080/2162402X.2022.2088467

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