Ibuprofen Treatment Reduces the Neuroinflammatory Response and Associated Neuronal and White Matter Impairment in the Growth Restricted Newborn

Ibuprofen Treatment Reduces the Neuroinflammatory Response and Associated Neuronal and White Matter Impairment in the Growth Restricted Newborn

Intrauterine growth restriction (IUGR) is a condition where the fetus does not achieve optimal growth, commonly caused by placental insufficiency. The chronic decrease in blood flow restricts oxygen and nutrient supply to the fetus, which can damage numerous organ systems, with the fetal brain being...

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Bibliographic Details
Main Authors: Julie A. Wixey, Kishen R. Sukumar, Rinaldi Pretorius, Kah Meng Lee, Paul B. Colditz, S. Tracey Bjorkman, Kirat K. Chand
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Physiology
Subjects:
placental insufficiency
growth retardation
fetal growth restriction
astrocytes
microglia
ibuprofen
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00541/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00541/full

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