Mycobacterium tuberculosis induces an atypical cell death mode to escape from infected macrophages.

Macrophage cell death following infection with Mycobacterium tuberculosis plays a central role in tuberculosis disease pathogenesis. Certain attenuated strains induce extrinsic apoptosis of infected macrophages but virulent strains of M. tuberculosis suppress this host response. We previously report...

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Bibliographic Details
Main Authors: Jinhee Lee, Teresa Repasy, Kadamba Papavinasasundaram, Christopher Sassetti, Hardy Kornfeld
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3069075?pdf=render