Autophagy compensates for Lkb1 loss to maintain adult mice homeostasis and survival

Liver kinase B1 (LKB1), also known as serine/threonine kinase 11 (STK11) is the major energy sensor for cells to respond to metabolic stress. Autophagy degrades and recycles proteins, macromolecules, and organelles for cells to survive starvation. To assess the role and cross-talk between autophagy...

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Bibliographic Details
Main Authors: Khoosheh Khayati, Vrushank Bhatt, Zhixian Sherrie Hu, Sajid Fahumy, Xuefei Luo, Jessie Yanxiang Guo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/62377