Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells

Specific Contributions of Cohesin-SA1 and Cohesin-SA2 to TADs and Polycomb Domains in Embryonic Stem Cells

Summary: Cohesin exists in two variants carrying either STAG/SA1 or SA2. Here we have addressed their specific contributions to the unique spatial organization of the mouse embryonic stem cell genome, which ensures super-enhancer-dependent transcription of pluripotency factors and repression of line...

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Bibliographic Details
Main Authors: Ana Cuadrado, Daniel Giménez-Llorente, Aleksandar Kojic, Miriam Rodríguez-Corsino, Yasmina Cuartero, Guillermo Martín-Serrano, Gonzalo Gómez-López, Marc A. Marti-Renom, Ana Losada
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719307077

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http://www.sciencedirect.com/science/article/pii/S2211124719307077

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