Transcriptomic and metabolomic analysis of the effects of Zhenwu decoction on kidney yang deficiency pattern in chronic kidney disease

Objective: To explore the kidney yang deficiency pattern (KYDP) in a chronic kidney disease (CKD) rat model and the mechanisms underlying the effects of Zhenwu decoction (ZWD) by conducting transcriptomic and metabolomic analyses. Methods: Adriamycin (ADR) combined with hydrocortisone (HC) was used...

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Bibliographic Details
Main Authors: Pengfei Zheng, Yunhua Liu, Xinjiang Zhang, Tingting Jiao, Yingjie Wu, Mengmeng Zhang, Xinxue Zhang, Zongjiang Zhao
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Journal of Traditional Chinese Medical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2095754823000017